About this product

Dosage and Administration
Adults (including the elderly) and children: To induce miosis, 1 or 2 drops should be used. In cases of emergency
treatment of acute narrow angle glaucoma, 1 drop should be used every 5 minutes until miosis is achieved. Each
Minims Pilocarpine eye drops unit should be discarded after a single use.

Contraindications
Conditions where pupillary constriction is undesirable such as acute iritis, pupillary block glaucoma, acute uveitis,
anterior uveitis, iridocyclitis, acute iritis and some forms of secondary glaucoma. Hypersensitivity to pilocarpine
nitrate. Retinal detachment; past history of retinal detachment or conditions that predispose to retinal detachment.
Use of soft contact lenses when administering pilocarpine eye drops.

Precautions
For topical ophthalmic use only. Not for injection. Retinal detachments have been caused in susceptible individuals
and those with pre-existing retinal disease; therefore, fundus examination is advised in all patients prior to the initiation
of therapy. If possible, treatment with long-acting miotics should be discontinued before surgery on the eye as there is
an increased risk of hyphaemia. Pilocarpine induces spasm of the ciliate muscle which may last up to two hours.
Topical miotics may precipitate bronchospasm in susceptible patients. Use with caution on an inflamed eye. Caution is
advised in patients with acute heart failure, bradycardia, coronary artery disease, bronchial asthma and other chronic
respiratory diseases, peptic ulceration, hypertension, urinary tract obstruction, Parkinson's disease and corneal
abrasions. Caution is advised in paediatric patients with primary congenital glaucoma.

Interactions
Belladonna alkaloids or cyclopentolate used ophthalmically may interfere with the miotic effects of pilocarpine and
may have their own mydriatic effects reduced.

Pregnancy & Lactation
Safety for use in pregnancy and lactation has not been established, therefore, use only when considered essential by
the physician.

Ability to Drive & Use Machines
Pilocarpine may cause transient blurring of vision on instillation and cause difficulty with dark adaptation. Patients
should be warned not to drive or operate hazardous machinery unless vision is clear.

Adverse Effects
Local effects include ciliary spasm, ocular pain and irritation, blurred vision, lachrymation, myopia, browache and
conjunctival vascular block. Lens opacities have occurred following prolonged use. Systemic adverse effects are rare.

Storage
Store at 2°C to 8°C. Protect from light.